Drug Discovery and Evaluation: Pharmacological Essays
Published by Springer
Updated to include the latest methods in molecular biology and genetic engineering
Practical guide for testing and evaluating the pharmacological effects of potential new drugs
Includes legal regulations of animal experiments
Fully searchable CD-ROM included
More than 1,000 assays in an easy-to-use and uniform format
This new edition has been updated to include the latest methods in molecular biology and genetic engineering. It contains a comprehensive selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance.
An accompanying, fully searchable CD-ROM allows easy identification of specific tests. An appendix with up-to-date guidelines and legal regulations for animal experiments in various countries will help the reader to plan experiments more effectively.
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